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  • Title: Prevotella brain abscess in a healthy patient with a patent foramen ovale: Case report.
    Author: Akimoto Y, Yanaka K, Onuma K, Nakamura K, Ishikawa E.
    Journal: Surg Neurol Int; 2021; 12():548. PubMed ID: 34877034.
    Abstract:
    BACKGROUND: Brain abscesses are relatively rare life-threatening infectious lesions often concomitant with a direct spillover of inflammation in the head or neck, hematogenous infections, and immunocompromised conditions. They rarely occur in adults without such predisposing factors. Prevotella is a well-known dental pathogen that very rarely causes brain abscesses. CASE DESCRIPTION: We report such an abscess in a 51-year-old man who was innately healthy and had no oral lesions. A comprehensive computed tomography examination of the chest, abdomen, and pelvis, was inconclusive but a transesophageal echocardiogram bubble study revealed a mild patent foramen ovale (PFO) that matched Grade 1 criteria. We deduced that the right-left shunt due to the PFO could have contributed to the brain infection and treated the patient successfully via surgical abscess aspiration and antibiotics. CONCLUSION: In case of a brain abscess occurring in healthy adults, it is essential to investigate the source of infection and the existence of an arterio-venous shunt, such as PFO.
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