These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Evidence for monoclonal T lymphocyte proliferation in angioimmunoblastic lymphadenopathy.
    Author: O'Connor NT, Crick JA, Wainscoat JS, Gatter KC, Stein H, Falini B, Mason DY.
    Journal: J Clin Pathol; 1986 Nov; 39(11):1229-32. PubMed ID: 3491840.
    Abstract:
    The arrangement of the T cell receptor and immunoglobulin genes was analysed in lymphoid tissue biopsy specimens from 25 cases of angioimmunoblastic lymphadenopathy. Nineteen cases showed a rearrangement of the gene coding for the beta chain of the T cell receptor, and in one case a clonal rearrangement of immunoglobulin genes was shown (in which the T cell receptor gene was in a germline configuration). These findings indicate that a monoclonal T cell proliferation is present in most cases of angioimmunoblastic lymphadenopathy, and they also correlate with the fact that some patients who present with this disorder subsequently develop a T cell lymphoma.
    [Abstract] [Full Text] [Related] [New Search]