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Title: Secondary cases of invasive disease caused by spread of Haemophilus influenzae type b. Author: Eskola J, Takala A, Käyhty H, Leinonen M, Kilpi T, Peltola H, Mäkelä PH. Journal: J Infect; 1987 May; 14(3):233-6. PubMed ID: 3495605. Abstract: Three 6-year-old girls were admitted to hospital within a period of 9 days because of invasive disease caused by Haemophilus influenzae type b (Hib). Two days after the index case contracted bacterial meningitis, her twin sister developed septicemia. Nine days after onset of illness in the index case, a day-care contact developed a febrile illness. The antibiograms of the bacterial strains isolated from cerebrospinal fluid or blood in the first two cases were identical; in the third case, blood cultures were negative but Hib antigen could be detected in serum and in urine. These cases illustrate the contagiousness of Hib disease. All household contacts of a case should be informed about the risk and their protection with rifampicin considered.[Abstract] [Full Text] [Related] [New Search]