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Title: COMORBID INTERNAL DISEASES IN MILITARY SERVANTS WHO HAVE SENSED THE EXPOSURE OF EXTREME FACTORS OF MILITARY SERVICE. Author: Voronko AA, Seliuk OV, Bohomolets OV. Journal: Probl Radiac Med Radiobiol; 2021 Dec; 26():339-356. PubMed ID: 34965559. Abstract: OBJECTIVE: to analyze comorbid pathology by methods of its quantitative assessment in servicemen exposed toextreme factors of military service (a set of factors of radiation accidents, the influence of modern armed conflictsand modern combat trauma without blood loss). MATERIALS AND METHODS: Studies of comorbid pathology were performed in 613 servicemen who were treated at theclinical base of the Ukrainian Military Medical Academy (UMMA) in National Military Medical Clinical Center «MainMilitary Clinical Hospital» NMMCC «MMCH» during 1989-2018 years. Soldiers who suffered from acute radiation sick-ness (ARS) in 1961 (n = 34), participants in the liquidation of the consequences of the Chornobyl catastrophe(PLCChC) 15 years after participating in the elimination of its consequences and in a later period (respectivelyPLCChC 1st group (n = 59) and the 2nd group (n = 337)). Soldiers are participants in the anti-terrorist operation(ATO)/Combined Forces (CFO) operation who did not receive modern combat injuries with blood loss (participants inthe ATO/CFO, n = 183). All servicemen did not have any diseases limiting their fitness capabilities for military serv-ice before being exposed to extreme factors of military service. A cumulative CIRS scale was used to comprehensive-ly assess comorbidity. RESULTS: With increasing time after participation in the elimination of the consequences of radiation accidents, thecourse of arterial hypertension (AH) is aggravated, but the dose-dependence of the severity of AH on the receivedradiation dose has not been established. The easier course of hypertension in ATO/CFO servicemen compared to ARSremote servicemen and group 2 PLCChC servicemen can be explained by their younger age at the time of the surveyand less time after exposure to extreme military service factors. In the military in the remote period after exposureto a complex of factors of radiation accidents, the frequency of diagnosing diseases by individual organs and bodysystem increases comparing to non-irradiated servicemen. The total number of disease severity scores on the cumu-lative scale of CIRS diseases is also higher. However, a dose-dependent effect of the severity of comorbid patholo-gy was also not found. These data indicate a higher prevalence of comorbid pathology in servicemen affected by acomplex of factors of radiation accf5idents, compared with participants in the anti-terrorist operation / environ-mental protection. However, the lower severity of comorbid pathology in ATO/CFO participants can also be explainedby their younger age at the time of the survey and less time after exposure to extreme factors of military service. CONCLUSIONS: For servicemen, with increasing time after participation in the elimination of the consequences ofradiation accidents, the course of hypertension without its dose dependence becomes more difficult. The total num-ber of disease severity scores on the cumulative scale of CIRS diseases in servicemen in the remote period after participation in the elimination of the consequences of radiation accidents is higher than in non-irradiated service-men. However, a dose-dependent effect of the severity of comorbid pathology was also not found. Meta: provedennia analizu komorbidnoï patologiï metodamy ïï kil'kisnoï otsinky u viĭs'kovosluzhbovtsiv, iaki zaz-naly vplyvu ekstremal'nykh faktoriv viĭs'kovoï sluzhby (kompleksu chynnykiv radiatsiĭnykh avariĭ, stresovykhvplyviv suchasnykh zbroĭnykh konfliktiv i suchasnoï boĭovoï travmy bez krovovtraty).Materialy ta metody. Doslidzhennia komorbidnoï patologiï provodyly u 613 viĭs'kovosluzhbovtsiv, iaki prokhody-ly likuvannia na klinichniĭ bazi Ukraïns'koï viĭs'kovo-medychnoï akademiï (UVMA) v Natsional'nomu viĭs'kovo-me-dychnomu klinichnomu tsentri «Golovnyĭ viĭs'kovyĭ klinichnyĭ gospital'» (NVMKTs «GVKG») protiagom 1989–2018rokiv. Viĭs'kovosluzhbovtsi, iaki perenesly gostru promenevu khvorobu (GPKh) v 1961 rotsi (n = 34), uchasnykylikvidatsiï naslidkiv Chornobyl's'koï katastrofy (ULNChK) cherez 15 rokiv pislia uchasti v likvidatsiï ïï naslidkiv i vbil'sh pizniĭ period (vidpovidno ULNChK 1-ï grupy (n = 59) ta 2-ï grupy, (n = 337)). Viĭs'kovosluzhbovtsi – uchasny-ky antyterorystychnoï operatsiï (ATO) / operatsiï Ob’iednanykh syl (OOS), iaki ne otrymuvaly suchasnoï boĭovoï trav-my z krovovtratoiu (uchasnyky ATO/OOS, n = 183). Vsi viĭs'kovosluzhbovtsi do togo, iak zaznaly vplyvu ekstremal'-nykh faktoriv viĭs'kovoï sluzhby, zakhvoriuvan', shcho obmezhuiut' ïkhniu prydatnist' do viĭs'kovoï sluzhby ne maly.Dlia kompleksnoï otsinky komorbidnosti bula vykorystana kumuliatyvna shkala zakhvoriuvan' CIRS.Rezul'taty. Zi zbil'shenniam chasu pislia uchasti v likvidatsiï naslidkiv radiatsiĭnykh avariĭ obtiazhuiet'sia perebig ar-terial'noï gipertenziï (AG), prote dozozalezhnosti tiazhkosti AG vid otrymanoï dozy radiatsiĭnogo vyprominiuvan-nia vstanovleno ne bulo. Bil'sh legkyĭ perebig AG u viĭs'kovosluzhbovtsiv – uchasnykiv ATO/OOS, porivniano zviĭs'kovosluzhbovtsiamy u viddalenomu periodi GPKh i viĭs'kovosluzhbovtsiamy – ULNChK 2-ï grupy, mozhe buty poias-nenyĭ ïkhnim molodshym vikom na moment obstezhennia i menshym chasom pislia vplyvu ekstremal'nykh faktorivviĭs'kovoï sluzhby. U viĭs'kovosluzhbovtsiv u viddalenomu periodi pislia vplyvu kompleksu chynnykiv radiatsiĭnykhavariĭ zbil'shuiet'sia chastota diagnostuvannia zakhvoriuvan' za okremymy organamy i systema organizmu, nizh u ne-oprominenykh viĭs'kovosluzhbovtsiv. Sumarna kil'kist' baliv tiazhkosti zakhvoriuvan' za kumuliatyvnoiu shkaloiuzakhvoriuvan' CIRS u nykh takozh vyshcha. Prote dozozalezhnogo efektu tiazhkosti komorbidnoï patologiï takozh vsta-novleno ne bulo. Tsi dani svidchat' pro bil'shu poshyrenist' komorbidnoï patologiï u viĭs'kovosluzhbovtsiv, iaki zaz-naly vplyvu kompleksu chynnykiv radiatsiĭnykh avariĭ, porivniano z uchasnykamy ATO/OOS. Odnak mensha tiazhkist'komorbidnoï patologiï v uchasnykiv ATO/OOS takozh mozhe buty poiasnena ïkhnim molodshym vikom na moment obste-zhennia i menshym chasom pislia vplyvu ekstremal'nykh faktoriv viĭs'kovoï sluzhby.Vysnovky. U viĭs'kovosluzhbovtsiv zi zbil'shenniam chasu pislia uchasti v likvidatsiï naslidkiv radiatsiĭnykh avariĭobtiazhuiet'sia perebig AG bez ïï dozozalezhnosti. Sumarna kil'kist' baliv tiazhkosti zakhvoriuvan' za kumuliatyvnoiushkaloiu zakhvoriuvan' CIRS u viĭs'kovosluzhbovtsiv u viddalenomu periodi pislia uchasti v likvidatsiï naslidkivradiatsiĭnykh avariĭ vyshcha, anizh u neoprominenykh viĭs'kovosluzhbovtsiv. Prote dozozalezhnogo efektu tiazhkostikomorbidnoï patologiï takozh vstanovleno ne bulo.[Abstract] [Full Text] [Related] [New Search]