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  • Title: Comparative antibacterial activity of the new oral cephalosporin BMY-28100.
    Author: Kayser FH.
    Journal: Eur J Clin Microbiol; 1987 Jun; 6(3):309-12. PubMed ID: 3497804.
    Abstract:
    The in vitro activity of BMY-28100 was compared with that of four other oral cephalosporins against gram-positive cocci, Branhamella catarrhalis and Haemophilus influenzae. BMY-28100 showed 5-20 times better activity against staphylococci and streptococci. Methicillin-resistant staphylococci and enterococci were resistant to the drug. Branhamella catarrhalis and Haemophilus influenzae strains were moderately susceptible. Time-kill curve studies showed BMY-28100 to be equally as active as benzylpenicillin, amoxycillin, flucloxacillin and cefaclor. By virtue of its in vitro spectrum, BMY-28100 can be considered a potentially useful agent for treatment of respiratory tract infections.
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