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  • Title: [Embryogenesis of the human pharyngeal tonsil].
    Author: Khlystova ZS, Savenko VA.
    Journal: Arkh Anat Gistol Embriol; 1987 Jun; 92(6):32-5. PubMed ID: 3498469.
    Abstract:
    By means of histological, histochemical, immunological and morphometric methods 78 pharyngeal tonsils of human embryos at the age of 12-40 weeks have been investigated. The character of the organ's anlage at 12-14 weeks of development as longitudinal folds on the dorsal wall of the rhinopharynx and changes in correlation of the lymphoid and epithelial tissues are presented in the process of the tonsil embryogenesis. Occupation of the organ with lymphocytes takes place on the 16th week of development. The embryos possess already two classes of T- and B-lymphocytes and their subclasses: auto-E-RFC, EAC-RFC, IgM and IgG positive cells; their kinetics is demonstrated in the process of the organ's development. A comparison on lymphocyte quantity, participating in cell-dependent immunity of the tonsil in fetuses, children and mature persons is presented.
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