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  • Title: Synthesis and pharmacological properties of some 2-substituted 1-(3-pyridyl)-1,2,3,4-tetrahydro-beta-carbolines.
    Author: Misztal S, Boksa J, Chojnacka-Wójcik E, Tatarczyńska E, Lewandowska A.
    Journal: Pol J Pharmacol Pharm; 1987; 39(1):97-103. PubMed ID: 3499603.
    Abstract:
    Six derivatives of 2-aminoacetyl-1,2,3,4-tetrahydro-beta-carboline (2a-f) were obtained, which yielded as a result of reduction with LiAlH4 six respective 2-aminoethyl-derivatives (3a-f). Pharmacological studies revealed that compounds 2f, 3e and 3f have sedative properties. None of the compounds possesses neuroleptic, antidepressive, anxiolytic, analgesic or anticonvulsant properties.
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