These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Dissociation of tdic chromosomes: about a t(15;18)(p11;p11) leading to 18p monosomy.
    Author: Garcia-Esquivel L, Rivera H, Sanchez-Corona J, Ramirez ML, Jimenez M, Cantú JM.
    Journal: Ann Genet; 1987; 30(2):94-7. PubMed ID: 3499849.
    Abstract:
    A 10-month-old girl with monosomy due to a de novo 45,XX,-15,-18,+tdic(15;18)(p11;p11) karyotype is described. The abnormal chromosome underwent dissociation into two telocentrics in 5/200 (2.5%) metaphases. This and other comparable instances indicate that, in addition to criss-cross separation of the dicentric chromatids, the characteristics of the anomalous reunion also influence the rate of dissociation. Besides, the mean maternal (31.2) and paternal (35.1) ages in this subtype of 18p monosomy are significantly increased.
    [Abstract] [Full Text] [Related] [New Search]