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  • Title: Hydrogel-Based Sensor Networks: Compositions, Properties, and Applications-A Review.
    Author: Sun X, Agate S, Salem KS, Lucia L, Pal L.
    Journal: ACS Appl Bio Mater; 2021 Jan 18; 4(1):140-162. PubMed ID: 35014280.
    Abstract:
    Hydrogels are three-dimensional porous polymeric networks prepared by physical or chemical cross-linking of hydrophilic molecules, which can be made into smart materials through judicious chemical modifications to recognize external stimuli; more specifically, this can be accomplished by the integration with stimuli-responsive polymers or sensing molecules that has drawn considerable attention in their possible roles as sensors and diagnostic tools. They can be tailored in different structures and integrated into systems, depending on their chemical and physical structure, sensitivity to the external stimuli and biocompatibility. A panoramic overview of the sensing advances in the field of hydrogels over the past several decades focusing on a variety protocols of hydrogel preparations is provided, with a major focus on natural polymers. The modifications of hydrogel composites by incorporating inorganic nanoparticles and organic polymeric compounds for sensor applications and their mechanisms are also discussed.
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