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  • Title: [Characteristics of the mechanisms of the immune response in typhoid fever and the bacterial carrier state].
    Author: Pogorel'skaia LV, Kirzon SS, Cheredeev AN, Il'inskiĭ IuA, Snisar' NA.
    Journal: Zh Mikrobiol Epidemiol Immunobiol; 1987 Nov; (11):68-72. PubMed ID: 3501649.
    Abstract:
    During the acute period of typhoid fever, as well as in the early and, partially, late convalescence periods, a considerable increase in the level of T-lymphocytes and their helper activity and, in some cases, in the number of B- and D-cells and the populations of neutrophils with receptors for C3 and Fc IgG was observed. In chronic carriers immune shifts of a different character have been recorded: an increase in suppressor activity and a decrease in the number of the above-mentioned neutrophils. These data prompt the use of immunological criteria for the prediction of chronic carrier state in typhoid fever.
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