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  • Title: Synthesis and analgesic antiinflammatory activities of 2-aryl-ethenyl-4-aryl-thiazole-5-acetic acids.
    Author: Bonina F, Guerrera F, Sarvà MC, Siracusa MA, Caruso A, Leone MG, Amico Roxas M.
    Journal: Farmaco Sci; 1987 Dec; 42(12):905-13. PubMed ID: 3502406.
    Abstract:
    A series of fifty-five 2-aryl-ethenyl-4-aryl-thiazole-5-acetic acids (IV-LVIII) were synthesized and evaluated for analgesic and antiinflammatory activities. Most of the synthesized compounds showed a good analgesic activity whereas some exhibited significant antiinflammatory activity.
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