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  • Title: Synthesis and antiinflammatory activity of some N-(5-substituted indole-3-ylglyoxyl)amine derivatives.
    Author: Da Settimo A, Primofiore G, Marini AM, Mori C, Franzone JS, Cirillo R, Reboani C.
    Journal: Farmaco Sci; 1987 Jan; 42(1):17-26. PubMed ID: 3502565.
    Abstract:
    The synthesis of some amidic derivatives, obtained by condensation of various 5-substituted indoleglyoxylchlorides with physiologically important amines as tyramine, tryptamine and 5-aminouracil, is described. The preparation of one glycolyl derivative is also reported. Study of analgesic and antiinflammatory properties has shown only a feeble activity of these compounds.
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