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  • Title: Sudden onset of confusion with severe exacerbation of parkinsonism during levodopa therapy.
    Author: Sage JI, Duvoisin RC.
    Journal: Mov Disord; 1986; 1(4):267-70. PubMed ID: 3504249.
    Abstract:
    Two patients with Parkinson's disease presented with unprovoked, abrupt onset of hallucinations, confusion and the simultaneous worsening of parkinsonian symptoms. This clinical syndrome appears to be a rare complication of dopaminergic therapy since improvement occurred gradually with reduction of Sinemet dosage.
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