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  • Title: Characterization of cadmium-binding proteins detected in rat liver by the western blotting technique.
    Author: Aoki Y, Suzuki KT.
    Journal: J Biochem Toxicol; 1987; 2():67-71. PubMed ID: 3508480.
    Abstract:
    Out of the three cadmium-binding proteins (CD-BPs) in rat liver parenchyma (40K, 29K, and 24K CdBPs), the 40K Cd-BP showed the highest affinity for cadmium (Cd), with a dissociation constant (KD) of 1.2 x 10(-8) M. This is in between the affinity of human serum albumin KD = 3.8 x 10(-5) M) and metallothionein (KD = less than 10(-11)). These Cd-BPs may be responsible for hepatic sequestration of cadmium.
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