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  • Title: Severe Cervical Kyphosis and Spondyloptosis with Myelopathy in Larsen Syndrome: A Report of 2 Cases.
    Author: Merrill RK, Ishmael TG, Samdani AF, Hwang SW, Pahys JM.
    Journal: JBJS Case Connect; 2021 Aug 04; 11(3):. PubMed ID: 35102030.
    Abstract:
    CASE: Two patients (ages 5 and 14 years) with Larsen syndrome and severe cervical kyphosis (patient 1) and spondyloptosis (patient 2), as well as complete anterior-posterior dissociation of the cervical spine, presented with severe, progressive myelopathy. Both patients underwent preoperative halo-gravity traction to slowly reduce the deformity followed by staged anterior-posterior decompression and fusion. Both patients demonstrated complete return of neurologic function. CONCLUSION: Patients with Larsen syndrome should be screened for cervical deformity at the time of diagnosis. Proper screening will facilitate early detection and treatment of significant deformities to prevent neurologic deterioration, which can be catastrophic in these patients.
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