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  • Title: Renal function after nephrectomy for donor organs.
    Author: O'Donnell D, Seggie J, Levinson I, Meyers AM, Botha JR, Myburgh JA, Cohen M, Duff JH, Thorsell R.
    Journal: S Afr Med J; 1986 Feb 01; 69(3):177-9. PubMed ID: 3511548.
    Abstract:
    Thirty-three living related kidney donors were investigated at a mean of 5.8 years after donor nephrectomy (range 3-18 years) to detect late adverse effects. They were evaluated for hypertension, the presence of proteinuria and renal dysfunction as assessed by serum creatinine value and creatinine clearance. There was a significant rise in both diastolic blood pressure and serum creatinine levels and a trend towards significance in the decline in creatinine clearance. Eleven individuals had diastolic blood pressure greater than or equal to 90 mmHg but only 1 required treatment. Although the rise in serum creatinine reached significance the mean serum creatinine (104.91 mumol/l) remained within the normal range. Two patients showed a minimal rise in proteinuria. The overall results confirm that kidney donation is safe and indicate that there are no significant late sequelae.
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