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  • Title: Ectopic beta-human chorionic gonadotropin production by bladder urothelial neoplasia.
    Author: Shah VM, Newman J, Crocker J, Chapple CR, Collard MJ, O'Brien JM, Considine J.
    Journal: Arch Pathol Lab Med; 1986 Feb; 110(2):107-11. PubMed ID: 3511880.
    Abstract:
    Endocrine manifestations are rarely observed in bladder urothelial neoplasia. To our knowledge, only 11 cases of choriocarcinoma have been reported in this site, and recently the production of beta-human chorionic gonadotropin has been demonstrated in these tumors by applying the immunoperoxidase technique. Of 104 transitional cell neoplasms of the bladder, we demonstrated by the indirect immunoperoxidase technique beta-human chorionic gonadotropin production in 12 neoplasms, 11 of which were grade 3 and 4 transitional cell carcinomas.
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