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  • Title: Antibiotic prophylaxis in cesarean section. Comparison of intrauterine lavage and intravenous administration.
    Author: Donnenfeld AE, Otis C, Weiner S.
    Journal: J Reprod Med; 1986 Jan; 31(1):15-8. PubMed ID: 3512820.
    Abstract:
    Intrauterine irrigation with a cefazolin solution at cesarean section was compared with intravenous cefazolin administration for prophylaxis against post-cesarean-section endomyometritis in a randomized, controlled, prospective fashion. There were no statistically significant differences in the incidence of infection between the lavage and intravenous groups. The incidence of endomyometritis was 37% in the lavage group and 29% in the intravenous (P = NS). Intrauterine cefazolin lavage is safe, effective, time saving and more cost effective than intravenous cefazolin in preventing post-cesarean-section endomyometritis.
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