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  • Title: [Rules of acupoint selection in treatment of erectile dysfunction with acupuncture and moxibustion based on data mining technology].
    Author: Zhou X, Yang JY, Shi R, Ding MR, Shen P.
    Journal: Zhongguo Zhen Jiu; 2022 Feb 12; 42(2):215-20. PubMed ID: 35152590.
    Abstract:
    Data mining technology was adopted to analyze the rules of acupoint selection in treatment of erectile dysfunction with acupuncture and moxibustion. All of the articles for acupuncture and moxibustion in treatment of erectile dysfunction were searched from the databases, i.e. Chinese national knowledge infrastructure (CNKI), Wanfang database, VIP, Chinese biomedical literature database (SinoMed) and PubMed, and the clinical trials on erectile dysfunction treated with acupuncture and moxibustion were screened. The database was set up by using Excel 2019 and input into R 4.0.3, and then, the therapeutic method, use frequency of acupoint, meridian tropism, collection visualization analysis, cluster analysis and association rule analysis were summarized. A total of 240 articles were included, with 516 prescriptions and 145 acupoints involved. The methods for treatment of erectile dysfunction included acupuncture and moxibustion therapy, acupuncture, acupoint injection, electroacupuncture, etc. The acupoints with high use frequency were Guanyuan (CV 4), Shenshu (BL 23), Sanyinjiao (SP 6), Mingmen (GV 4), Zusanli (ST 36), Zhongji (CV 3), Ciliao (BL 32), Qihai (CV 6), Taixi (KI 3) and Taichong (LR 3). The meridians involved with high frequency were the bladder meridian of foot-taiyang, the conception vessel, the spleen meridian of foot-taiyin, etc. The common acupoint combination was Shangliao (BL 31), Zhongliao (BL 33), Ciliao (BL 32), Xialiao (BL 34) and Sanyinjiao (SP 6), Shenshu (BL 23), Guanyuan (CV 4). In association rule analysis (confidence ≥ 90%, support ≥ 20%), there were 27 association rules in total. The acupoint combination with the highest support referred to "Shenshu (BL 23), Sanyinjiao (SP 6)→Guanyuan (CV 4)" (support 46.7%) and the acupoint combination with the highest confidence was "Sanyinjiao (SP 6), Qihai (CV 6)→Guanyuan (CV 4)" (confidence 98.0%). The acupoints could be divided into 5 effective clusters. Acupuncture and moxibustion therapy has a certain of rules of acupoint selection in treatment of erectile dysfunction, which provides the evidences for modern clinical trial and treatment. 采用数据挖掘技术分析针灸治疗阳痿的取穴规律。计算机检索中国期刊全文数据库（CNKI）、万方数据知识服务平台（Wanfang）、维普资讯中文期刊服务平台（VIP）、中国生物医学文献数据库（SinoMed）及PubMed数据库针灸治疗阳痿的临床研究文献。通过Excel 2019建立数据库，并导入R 4.0.3软件，进行治疗方法、腧穴频次与归经、集合可视化分析、聚类分析及关联规则分析。共纳入有效文献240篇，涉及516个针灸处方、145个腧穴；针灸治疗阳痿的方法主要包括针灸（针刺+灸法）、针刺、穴位注射（水针）、电针等；高频应用腧穴分别是关元、肾俞、三阴交、命门、足三里、中极、次髎、气海、太溪、太冲；应用频次较高的经脉分别为足太阳膀胱经、任脉、足太阴脾经等；常用的腧穴组合为上髎、中髎、次髎、下髎和三阴交、肾俞、关元；关联规则分析（置信度≥90%，支持度≥20%）共得到27个关联规则，支持度最高的组穴为“肾俞，三阴交→关元”（支持度为46.7%），置信度最高的组穴为“三阴交，气海→关元”（置信度为98.0%）；腧穴可分为5个有效聚类群。针灸治疗阳痿选穴遵循一定规律，可为现代临床研究及治疗提供依据。.
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