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  • Title: Neuropeptide Y and the innervation of the human eye.
    Author: Stone RA.
    Journal: Exp Eye Res; 1986 Apr; 42(4):349-55. PubMed ID: 3519261.
    Abstract:
    Using the indirect immunohistochemical technique, neuropeptide Y as found in human ocular nerves. While limbal blood vessels were innervated and a few nerves were seen in the trabecular meshwork, the cornea proper contained no immunoreactive nerve fibers. Neuropeptide Y-like immunoreactive nerves supplied the iris dilator muscle and, to a lesser extent, the iris sphincter. Immunoreactive nerve fibers were present within the ciliary muscle and the ciliary processes. Neuropeptide Y-like immunoreactive choroidal nerve fibers were frequently associated with blood vessels. The apposition of immunoreactive nerve fibers and melanocytes occurred throughout the uvea. The distribution of neuropeptide Y-like immunoreactive nerves in the eye closely parallels the adrenergic innervation. Evidence linking neuropeptide Y to the ocular sympathetic innervation is discussed.
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