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  • Title: [Antibodies against ds-DNA in systemic lupus erythematosus--value for diagnosis and determination of activity].
    Author: Geissler K, Graninger W.
    Journal: Immun Infekt; 1986 May; 14(3):119-20. PubMed ID: 3519437.
    Abstract:
    The specificities and sensitivities of 3 methods for detection of anti-ds-DNA-antibodies were investigated in 32 SLE-patients and 95 control patients with ANA greater than or equal to 1:100. The sensitivities of CL-IF-assay, filter-RIA and EIA were 47%, 78% and 87%, respectively. The according specificities were 96%, 88% and 84%. In contrast to the CL-IF-assay, the filter-RIA as well as the EIA are of major clinical importance in monitoring SLE-patients.
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