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  • Title: Transferable antibiotic resistance in enterobacteriaceae isolated from urinary tract infections in general practice.
    Author: Poston SM, Maclaren DM, Thornton VG.
    Journal: Zentralbl Bakteriol Orig A; 1978 Apr; 240(3):326-33. PubMed ID: 352037.
    Abstract:
    138 different coliform isolates from patients with UTI in 2 General Practices in Stockport, England, showed an incidence of drug resistance of 36%: 47% of these strains transferred resistance to E. coli K12. Multiple resistance, i.e. resistance to more than 2 drugs occurred in more than a quarter of resistant isolates and sulphonamide resistance was most common. More than twice as many strains in this series (1973--74) were sulphonamide resistant compared with a previous survey (1968--70). MIC values of R+ resistant isolates were much higher with sulphonamide resistant strains than the probable urine levels during therapy, but the situation with ampicillin and tetracycline levels was variable.
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