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  • Title: [Work of breathing in spontaneous respiration with continuous positive airway pressure].
    Author: Kellermann W, Summa Y, Rupprecht H, Unertl K, Jensen U.
    Journal: Schweiz Med Wochenschr; 1986 Apr 26; 116(17):561-5. PubMed ID: 3520809.
    Abstract:
    In postoperative respiratory failure continuous positive airway pressure (CPAP), besides improving pulmonary gas exchange, influences respiratory mechanics. Elastic and flowresistive components of respiratory work were measured in intensive care patients being weaned from the respirator. Measured values during breathing with a continuous-flow CPAP system with elastic reservoir were compared with those for O2 breathing via T-tube. Under CPAP total breathing work and resistance were reduced. Compliance, tidal volume and respiratory frequency did not change significantly. The reduction in respiratory work was primarily due to decreased nonelastic work associated with a decrease in resistance. Thus, on weaning from mechanical ventilation using a reservoir-CPAP system, the respiratory work was reduced in comparison to O2 breathing via T-tube.
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