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  • Title: [Analysis on rules of acupoint compatibility and application characteristics in acupuncture treatment of migraine based on complex network technique].
    Author: Han P, Wen J, Wu HH, Wang RQ, Shi J, Xing HJ, Zhang XQ, Jia CS, Li XF.
    Journal: Zhen Ci Yan Jiu; 2022 Feb 25; 47(2):171-6. PubMed ID: 35218629.
    Abstract:
    OBJECTIVE: To analyze the compatible rules of acupoints in the treatment of migraine with acupuncture and moxibustion based on complex network technique so as to provide a reference for composing best acupoint recipes. METHODS: Clinical papers about acupuncture treatment of migraine published from January of 2010 to October of 2020 were searched from Chinese and English databases including CNKI, Wanfang, VIP and Pubmed by using keywords of acupuncture, moxibustion and migraine. According to our inclusive and exclusive criteria, the collected papers were screened out to set up a database. The SPSS Modeler 18.0 software was used to analyze the association rules of acupoints, and the Gephi 0.9.2 software was used to conduct a complex network analysis about the compatibility rules of acupoints and their application characteristics of moxibustion and needling methods in the treatment of migraine. RESULTS: In the end, 572 articles meeting the conclusive criteria were selected, and a total of 1 091 acupoint prescriptions for the treatment of migraine were extracted, including 230 acupoints with a total appea-rance frequency of 7 902. Those acupoints most frequently used were mainly attributed to the Gallbladder Meridian, with Fengchi (GB20) being the highest in the cumulative frequency. The association rule analysis showed that the highest supporting degree acupoints was GB20-Taiyang(EX-HN5). The highest levels of confidence were EX-HN5-Touwei(ST8), GB20-Baihui(GV20), and GB20-ST8. The analysis of complex network topology showed that a total of 17 acupoints including GB20, EX-HN5, Shuaigu(GB8), Taichong(LR3), GV20, Ashi point, etc. were the core node acupoints for acupuncture treatment of migraine. CONCLUSION: In the treatment of migraine, the acupoints selected are mainly distributed in the head region. When the specific acupoints chosen, the five Shu acupoints, Yuan (source) acupoints and the confluent acupoints of eight meridians are frequently used. In terms of composing acupoint recipes, the acupoints in the local and distant part of the body are often used in combination. These outcomes may have a certain guiding significance for clinical treatment of migraine. 目的：基于复杂网络技术分析针灸治疗偏头痛的腧穴配伍规律，为针灸临床治疗与研究偏头痛的选穴组方提供参考。方法：通过检索中国知网、万方数据知识服务平台、维普资讯中文期刊服务平台、PubMed近10年关于针灸治疗偏头痛的临床文献，根据纳入、排除标准筛选出相关文献，建立数据库。运用SPSS Modeler 18.0软件进行腧穴的关联规则分析，并利用Gephi 0.9.2软件进行复杂网络分析针灸治疗偏头痛的腧穴配伍规律及腧穴刺灸法应用特点。结果：最终筛选出572篇符合标准的文献，共提取1 091条针灸治疗偏头痛的处方，涉及230个腧穴，腧穴的总频次为7 902次。所使用腧穴以足少阳胆经为主，其中风池的累积运用频次最高。关联规则分析显示腧穴间支持度最高的是风池-太阳；置信度最高的是太阳-头维、风池-百会、风池-头维。通过复杂网络拓扑结构分析发现风池、太阳、率谷、太冲、百会、阿是穴等17个腧穴为针灸治疗偏头痛的核心节点腧穴。结论：针灸治疗偏头痛处方所选腧穴主要分布于头部，特定穴多选用五输穴、原穴以及八脉交会穴，在选穴和腧穴配伍方面注重远近配穴。.
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