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  • Title: Results of another trial of chemotherapy with and without hormones in patients with newly diagnosed metastatic prostate cancer.
    Author: Murphy GP, Huben RP, Priore R.
    Journal: Urology; 1986 Jul; 28(1):36-40. PubMed ID: 3523938.
    Abstract:
    From July, 1980, to June, 1983, 319 patients with newly diagnosed metastatic prostatic cancer were randomized to one of three treatment protocols: diethylstilbestrol (DES) or bilateral orchiectomy, cyclophosphamide plus 5-fluorouracil plus DES, and estramustine phosphate (Emcyt). Ninety-three per cent of 296 patients were eligible for evaluation. This report shows no difference in survival, disease-free progression time, or status regarding pain at entry. Other prognostic factors failed to reveal any difference within any of the treatment protocols.
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