These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Efficacy of combined treatment with oral and topical acyclovir in first episode genital herpes.
    Author: Kinghorn GR, Abeywickreme I, Jeavons M, Barton I, Potter CW, Jones D, Hickmott E.
    Journal: Genitourin Med; 1986 Jun; 62(3):186-8. PubMed ID: 3525386.
    Abstract:
    Fifty patients presenting with first episode genital herpes were randomly allocated to seven day treatment with either oral acyclovir plus 5% acyclovir cream or oral acyclovir plus matching placebo cream. Combined treatment with oral and topical acyclovir was associated with a shorter duration of itching in women alone (p = 0.04) but gave no clinical relief of other symptoms, the time to healing of lesions, or the subsequent recurrence rate. Concomitant topical treatment with 5% acyclovir cream confers no advantages on patients who receive oral acyclovir.
    [Abstract] [Full Text] [Related] [New Search]