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  • Title: Scopolamine effects in vestibular defensiveness.
    Author: Childs A.
    Journal: Arch Phys Med Rehabil; 1986 Aug; 67(8):554-5. PubMed ID: 3527109.
    Abstract:
    Disturbed vestibular function secondary to brain stem injury may result in postural gravitational insecurity, and aversion reactions or intolerance to movement. The Transderm scopolamine disc was applied in a double-blind, placebo-controlled study of five post-head-injury patients who underwent provocative vestibular stimulation such as turning in a wheelchair, head shaking, and the log roll. Four of the patients showed improvement in exquisite sensitivity to rotational movement. A surprise finding of improved truncal stability in two of the more severely injured patients indicates a potential usefulness of the scopolamine patch for patients with truncal ataxia.
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