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  • Title: [Effect of ethmozin and Ritmilen on microcirculatory hemostasis in patients with heart rhythm disorders].
    Author: Grigor'ev GI, Petrova TR.
    Journal: Farmakol Toksikol; 1986; 49(5):94-7. PubMed ID: 3533622.
    Abstract:
    Effects of ethmozine and ritmilen were studied in 75 patients with different disorders of cardiac rhythm predominantly proceeding in the form of extrasystole arrhythmia. The drugs were found to exert a distinct antiaggregant action on platelets and erythrocytes which was particularly pronounced at intravenous administration and transiently increased the number of leukocytes and their aggregation. A decrease of platelet aggregation was accompanied by an increase of their number and rejuvenascence of thrombocytogram. A marked antiarrhythmic effect was seen in 66% of patients, in the remaining patients cardiac extracontractions became more rare.
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