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  • Title: [Functional changes in the state of the insular system of animals after intravenous administration of diabetogenic factor].
    Author: Kudriashov BA, Ul'ianov AM, Liapina LA.
    Journal: Vopr Med Khim; 1986; 32(5):57-9. PubMed ID: 3535246.
    Abstract:
    Natural diabetogenic factor, which is albumin with molecular mass 60,000 Da, occurring in blood plasma of rats impaired with alloxan diabetes, caused a stable hyperglycemia, distinct decrease of insulin in blood and increased the body resistance to insulin in healthy animals. Activity of the diabetogenic factor was neutralized by heparin.
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