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  • Title: [Effect of tranquilizers on impulse conduction in the afferent pathways of visceral nerves].
    Author: Sinitsyn LN, Churiukanov VV.
    Journal: Farmakol Toksikol; 1979; 42(2):112-7. PubMed ID: 35365.
    Abstract:
    Experiments on pyrolaxon-immobilized cats evidence that diazepam produces depression of evoked potentials in the specific, nonspecific and associative brain structures upon an electric stimulation of the visceral and somatic nerves, and also with accoustic and photostimulation; Meprotan (meprobamate) in doses of 40-100 mg/kg neither changes nor increases, and in doses of 100-150 mg/kg, reduces the amplitude of evoked potentials and at the sme time forces down the arterial pressure. Amizyl (benactyzine) inhibits the potentials evoked by stimulation of the vagus. The amplitude of responses arising on stimulation of the inferior cardiac, celiac and sciatic nerves, and also with acoustic and photostimulation neither changes nor increases.
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