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  • Title: Modulation of lysosomal protease-esterase and lysozyme in Kupffer cells and peritoneal macrophages infected with Nocardia asteroides.
    Author: Black CM, Paliescheskey M, Beaman BL, Donovan RM, Goldstein E.
    Journal: Infect Immun; 1986 Dec; 54(3):917-9. PubMed ID: 3536752.
    Abstract:
    Virulent Nocardia asteroides reduces lysosomal acid phosphatase activity in murine macrophages. A computer-assisted imaging photometry system was used to quantitate lysozyme and nonspecific esterase-neutral protease levels within individual macrophages following ingestion of nocardiae. In contrast to acid phosphatase, lysozyme and esterase-neutral protease activity was either unchanged or increased following infection by increasing numbers of nocardial cells.
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