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  • Title: Give ears some respite from regular microsuctioning in bisphosphonate-induced osteonecrosis of the external ear canal.
    Author: Abelardo E, Jaramillo M.
    Journal: J Laryngol Otol; 2022 Oct; 136(10):1002-1004. PubMed ID: 35382918.
    Abstract:
    BACKGROUND: This paper reports a case series of three elderly patients who were regularly attending ENT clinic every four to six weeks for ear canal care to address chronic otitis externa. All three patients had been taking bisphosphonate alendronic acid for years, and it is suspected that this drug was partly to blame for the progression of their chronic ear conditions. RESULTS: Some improvements were noted when the bisphosphonate was discontinued. The regular microsuctioning, and application of topical antibiotics with steroids, provided temporary relief of symptoms. The present pandemic shut down the routine clinic and the patients were not seen for four to five months. On latest review, it was a surprise to see that their ears seemed to have significantly improved, with healthy re-epithelialisation. CONCLUSION: It is thus believed that excessive and repeated microsuctioning in bisphosphonate-induced osteonecrosis of that external ear canal can delay re-epithelialisation, and gradually prolonging the intervals between microsuctioning could help in overall resolution of the disease.
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