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  • Title: Low-dose etretinate in the maintenance of remission of palmoplantar pustular psoriasis.
    Author: White SI, Puttick L, Marks JM.
    Journal: Br J Dermatol; 1986 Nov; 115(5):577-82. PubMed ID: 3539171.
    Abstract:
    Twenty patients with palmoplantar pustular psoriasis were treated initially for 4 weeks with 70 mg etretinate daily. This led to clinical improvement and a significant fall in pustule count. The patients were then allocated randomly to 30 mg etretinate daily or placebo for a further 12 weeks. There was a rapid deterioration in the clinical condition and a rise in pustule count in the placebo group. The etretinate-treated group still showed clinical improvement and a significantly lower pustule count after 12 weeks. Clinical side-effects were few and adverse effects on liver function and serum lipids were not found.
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