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  • Title: [Evaluation of the size of the microsphere loss from the myocardium in rats in a chronic experiment].
    Author: Medvedev OS, Martynova ER, Akchurin RS, Khalatov VIu.
    Journal: Biull Eksp Biol Med; 1987 Jan; 103(1):8-10. PubMed ID: 3542076.
    Abstract:
    The loss of radioactive microspheres (15 microns in diameter) from the rat myocardium was investigated during chronic experiment. Microspheres were injected to donor rats, the hearts were removed 20-30 min later and the number of microspheres trapped in the heart was determined on gamma-counter. After that the hearts were transplanted into the abdominal cavity of recipient rats using microsurgery technique. 5-24 days later the recipients were killed, the transplanted hearts were removed and radioactivity was measured again. It was shown that not more than 10% of microspheres were lost from the myocardium over a 5-24-day period, with the value of microsphere loss independent of the time period.
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