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  • Title: [Comparative studies of IgE content of the gastric mucosa in various forms of gastritis].
    Author: Dukat H, Dumke K, Niedobitek F, Volkheimer G.
    Journal: Z Gastroenterol; 1986 Nov; 24(11):667-72. PubMed ID: 3544540.
    Abstract:
    The problem of the pathogenetic significance of IgE-mediated inflammatory processes in simple unspecific gastritis was studied in mucosal biopsies of 396 cases with unequivocal histological classification. The results demonstrate that only in acute and erosive gastritis high IgE cell counts are found, thus, indicating a pathogenetic significance. Furthermore the statistical evaluation showed a parallel age distribution of IgE containing cells in the four biopsy groups. Mucosal biopsies from patients 40-65 years of age exhibited higher IgE cell counts than younger and older persons. These results suggest that there is a higher IgE-reactivity in the middle age.
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