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  • Title: Ameloblastic carcinoma: A case report and evaluation.
    Author: Manchanda AS, Narang RS, Nagi RS.
    Journal: J Oral Maxillofac Pathol; 2022 Feb; 26(Suppl 1):S63-S67. PubMed ID: 35450254.
    Abstract:
    Malignant odontogenic neoplasms are extremely challenging to study due to their rarity and variable clinical presentations. Ameloblastic carcinoma (AC) is one such odontogenic tumor which has been the subject of controversy, in part because of its scarcity, complicated by confusion in terminology along with complexity in classification. Histologic features of AC resemble tumor cells of ameloblastoma but exhibit cellular atypia. Surgical resection for this kind of lesion, leaving at least a 2 cm free margin coupled with neoadjuvant radiotherapy, might prove fruitful results. The current paper reports a case of an extraosseous variant of AC which posed a diagnostic challenge due to variable presentations histopathologically, suggesting the need for evidence-based case studies and molecular workup for a better therapeutic and prognostic insight.
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