These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Isolation and study of the biological properties of substances stimulating levorin biosynthesis in a mixed actinomycete and yeast culture].
    Author: Iakovleva EP, Alekseeva LE.
    Journal: Antibiot Med Biotekhnol; 1986 Nov; 31(11):830-5. PubMed ID: 3545067.
    Abstract:
    Active components responsible for increased synthesis levels of levorin, a polyenic antibiotic in mixed cultures of an actinomycete and a yeast-like fungus C. tropicalis were isolated from the fermentation broth. Component I identified as succinic acid increased the levels of the antibiotic production by 40-50 per cent. Component II found to be lactic acid increased the antibiotic production levels by 20 per cent. Component III, a mixture of nonidentified substances of the amine nature stimulated biosynthesis of levorin by 20-25 per cent. Addition of a mixture of succinic acid and N-methyl glucosamine to the nutrient medium provided increase of the antibiotic activity of the fermentation broth up to 175-185 per cent as compared to the control.
    [Abstract] [Full Text] [Related] [New Search]