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  • Title: [Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome) Part I. Pathophysiology, clinical symptoms and recommend screening for vascular malformations].
    Author: Adam Z, Brančiková D, Romanová G, Pour L, Krejčí M, König J, Nebeský T, Adamová Z, Štork M, Krejčí M, Ševčíková S, Eid M, Král Z.
    Journal: Vnitr Lek; 2021; 67(6):339-344. PubMed ID: 35459376.
    Abstract:
    Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is an autosomal dominant disorder that causes abnormal blood vessel formation. Patients with HHT may have telangiectasias and later may develop arteriovenous malformations in various organs. Pacients suffer from many complications caused by the malformations and therefore by patients with HHT must by performed screening of this arteriovenous malformations. Optimal treatment of this malformations is best delivered throught a multidisciplinary approach. Farmacological treatment is described in next paper.
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