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  • Title: Two Distinct Cases of Adult-onset Kawasaki Disease.
    Author: Onoki T, Metoki T, Iwasawa S, Kawano K, Kimura M, Kure S, Ota C.
    Journal: Intern Med; 2022 Dec 01; 61(23):3525-3529. PubMed ID: 35466164.
    Abstract:
    Kawasaki disease (KD) is a systemic vasculitis syndrome that mostly affects children under 4 years old. Among the reported KD cases, only 1% were over 10 years old. We herein report 2 cases of adult-onset KD (AKD) in 19- and 17-year-old boys diagnosed with a persistent fever and cervical lymphadenitis. Both patients showed cardiac complications, such as coronary artery dilation and myocarditis. Repeated intravenous immunoglobulin therapy was effective in the 19-year-old, while plasma exchange therapy was needed for the 17-year-old, with no sequelae noted at discharge. KD should be considered as a differential diagnosis for persistent fever in adults.
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