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  • Title: Allergy to Radiocontrast Dye.
    Author: Brockow K.
    Journal: Immunol Allergy Clin North Am; 2022 May; 42(2):391-401. PubMed ID: 35469625.
    Abstract:
    Radiocontrast media (RCM) are common elicitors of immediate and nonimmediate hypersensitivity reactions, manifesting predominantly as urticaria/anaphylaxis or exanthems, respectively. In the minority of patients with immediate hypersensitivity reactions to RCM allergy is demonstrated by positive skin tests. However, data show that assessment by an allergist/immunologist is beneficial for managing patients with previous immediate and nonimmediate hypersensitivity reactions. For future RCM-enhanced examinations in patients with previous reactions, structurally different, skin test-negative preparations should be applied. The efficacy of this strategy is confirmed by drug provocation tests or exposures confirming or excluding RCM hypersensitivity and demonstrating tolerability of alternative RCM.
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