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  • Title: [Pharyngeal viral population in 3- to 6-year-old children before and after influenza immunization using the NIVGRIP vaccine administered orally].
    Author: Pârvu C, Petrescu A, Coban V.
    Journal: Virologie; 1986; 37(4):263-7. PubMed ID: 3548031.
    Abstract:
    Immunofluorescence techniques were used to investigate the incidence of viral antigens in exfoliated pharyngeal cells collected from 94 3-6-year-old children living in a collectivity, vaccinated by oral route with NIVGRIP inactivated influenza vaccine. The vaccination resulted in a significant decrease of IF-positive subjects from 80% before to 39% after immunization, indicating a fall in the virus carriage level. The percentage of children in which two or more viral antigens were found also decreased from 72% to 33%. As regards the incidence of different viruses, the complete disappearance of influenza antigens and a marked decrease of the other investigated viral agents were recorded.
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