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  • Title: [Giant hamartomatous nevus of undescribed complexity (development of an infiltrating malignant melanoma)].
    Author: Kaplan H, Lacentre E.
    Journal: Med Cutan Ibero Lat Am; 1986; 14(6):413-20. PubMed ID: 3550317.
    Abstract:
    A case is reported of complex hamartoma with the aspect of a giant pigmented nevus, localized in one of the lower extremities. Histological examination revealed the involvement of different embryonal layers in order to give rise to dissimilar types of nevi: flat pigmented nevus, intradermal cellular nevus, epidermal verrucous nevus, Jadassohn's sebaceous nevus; Hoffman-Zurhelle's superficial lipomatous nevus, and fibrous hamartoma of the manifested at infancy. This malformation and more specifically the nevus cells constitute the subsequent transformation into an infiltrating malignant blastoma (malignant melanoma).
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