These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Biopsy findings in kidney transplants after treatment with cyclosporin A].
    Author: Nizze H, Gokel JM, Lang W, Mihatsch MJ.
    Journal: Zentralbl Allg Pathol; 1986; 132(5-6):423-33. PubMed ID: 3551394.
    Abstract:
    51 renal transplant biopsies of 37 patients immunosuppressed with Cyclosporin A were histologically reevaluated. Lesions related as well as unrelated to Cyclosporin A treatment were found. Cyclosporin A related findings corresponding to the so-called Cyclosporin A nephropathy were divided into early postoperative (diffuse fibrosis), acute (toxic tubulopathy and others) and chronic changes (arteriolopathy, striped fibrosis with tubular atrophy). Since there is often a combination of Cyclosporin A related and unrelated lesions, it is necessary to define the main lesion in the individual case. Accordingly, the following diagnostic groups were present in the biopsies: Cyclosporin A nephropathy (19 cases), rejection nephropathy (18), rejection and Cyclosporin A nephropathy (9), acute renal failure (3) and other diagnoses (2 cases). For the further management of the patients, the exact diagnosis of Cyclosporin A related and unrelated pathology is important in renal biopsies.
    [Abstract] [Full Text] [Related] [New Search]