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  • Title: Screening for sickle cell trait: the Veterans Administration National Sickle Cell Program.
    Author: Meyer LM, Adams JG, Steinberg MH, Miller IE, Stokes N.
    Journal: Am J Hematol; 1987 Apr; 24(4):429-32. PubMed ID: 3551591.
    Abstract:
    Results of the Veterans Administration Sickle Cell Program for a period of 10 years are presented. We screened 370,250 patients; 404,341 attended educational sessions, and 38,347 had individual counseling sessions. Sickle cell trait was present in 6.4% of patients, and HbC trait was present in 1.8%. The clinically significant disorders HbSC disease, sickle cell anemia, and sickle beta thalassemia were present in 0.41% of individuals screened. A large number of uncommon variants were detected. The program enhanced the awareness of and the approach to evaluation of hemoglobinopathies.
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