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Title: Clarifications regarding bumetanide for neonatal seizures. Author: Staley KJ. Journal: Epilepsia; 2022 Jul; 63(7):1863-1867. PubMed ID: 35524444. Abstract: A recent Phase II randomized, controlled trial of bumetanide as an adjunctive treatment for neonatal seizures showed a robust efficacy signal and no evidence of toxicity. Concerns regarding bumetanide as an adjunctive anticonvulsant are addressed here. An adequately powered multi-institutional trial is needed to accurately determine efficacy.[Abstract] [Full Text] [Related] [New Search]