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  • Title: Clarifications regarding bumetanide for neonatal seizures.
    Author: Staley KJ.
    Journal: Epilepsia; 2022 Jul; 63(7):1863-1867. PubMed ID: 35524444.
    Abstract:
    A recent Phase II randomized, controlled trial of bumetanide as an adjunctive treatment for neonatal seizures showed a robust efficacy signal and no evidence of toxicity. Concerns regarding bumetanide as an adjunctive anticonvulsant are addressed here. An adequately powered multi-institutional trial is needed to accurately determine efficacy.
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