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  • Title: Hepatic effects of acetaminophen. Enhanced toxicity in alcoholics.
    Author: Maddrey WC.
    Journal: J Clin Gastroenterol; 1987 Apr; 9(2):180-5. PubMed ID: 3553308.
    Abstract:
    Alcoholic patients run an increased risk of developing hepatotoxicity from doses of acetaminophen within or only moderately above the recommended usual therapeutic doses. In this review I examine the scientific evidence and clinical observations that indicate such a heightened susceptibility of the alcoholic to acetaminophen-induced injury.
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