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  • Title: Structure of the repressor-operator complex of bacteriophage 434.
    Author: Anderson JE, Ptashne M, Harrison SC.
    Journal: Nature; ; 326(6116):846-52. PubMed ID: 3553959.
    Abstract:
    The crystal structure of a specific complex between the DNA-binding domain of phage 434 repressor and a synthetic 434 operator DNA shows interactions that determine sequence-dependent affinity. The repressor recognizes its operators by its complementarity to a particular DNA conformation as well as by direct interaction with base pairs in the major groove.
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