These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The implications of decreased performance of new generation gamma-cameras on the interpretation of 131I-Hippuran renal images.
    Author: Zuckier LS, Axelrod MS, Wexler JP, Heller SL, Blaufox MD.
    Journal: Nucl Med Commun; 1987 Jan; 8(1):49-61. PubMed ID: 3554052.
    Abstract:
    Several patients with renal failure in whom the kidneys were more clearly imaged with 99Tcm-DTPA than 131I-Hippuran were recently observed. We have postulated that our newer generation gamma-cameras have a reduced capacity to image 131I in comparison to older generation cameras. This hypothesis was tested by comparing representative older and newer imaging systems. Full-width tenth-maximum 99Tcm linespread functions were 1.20 and 1.55 cm for the older and newer cameras, respectively. The 99Tcm count rate on the newer camera was 111% that of the older camera, and the observed kidney to background count ratios in a phantom model were virtually identical for the two cameras imaging a number of simulated 99Tcm count distributions. Full-width tenth-maximum 131I linespreads were 1.55 and 4.78 cm, respectively, on the older and newer cameras and the 131I count rate on the newer camera was 27% of the count rate on the older system. The phantom model demonstrated a consistently lower 131I perceived kidney to background count ratio on the newer gamma-camera compared to the older system. These findings should be considered in the interpretation of 131I-Hippuran studies on newer-generation equipment until revised criteria of interpretation have been established. Non-visualization of the kidney may not have the same prognostic implication using modern cameras as has been reported from studies with older generation detector systems.
    [Abstract] [Full Text] [Related] [New Search]