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  • Title: [Effect of lipid peroxidation on the insulin receptor in rat adipocytes].
    Author: Ivanov VV, Stennikova MP, Pereboeva LA, Udintsev NA.
    Journal: Ukr Biokhim Zh (1978); 1987; 59(2):57-61. PubMed ID: 3554677.
    Abstract:
    Lipid peroxidation is studied for its effect on insulin receptors in isolated rat adipocytes. The results suggest that addition of two peroxidants (3 mM cumene hydroperoxide and 0.2 mM Fe2+) leads to malondialdehyde accumulation and binding inhibition through insulin receptors quantity and affinity decrease.
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