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  • Title: [Effect of morphine and pentazocine on emotional-behavioral and hemodynamic nociceptive reactions].
    Author: Zaĭtsev AA, Ignatov IuD, Petriaevskaia NV.
    Journal: Farmakol Toksikol; 1987; 50(1):27-30. PubMed ID: 3556548.
    Abstract:
    Pentazocine (5-15 mg/kg) fails to change the period of latency in the rat tail-flick reaction at thermic stimulation but suppresses to the same extent as morphine (5 mg/kg) the emotional-pain response and enhances the reactions of arterial blood pressure during mechanical stimulation. Both prazosin and naloxone (1 mg/kg) abolished the activating effect of pentazocine on the arterial blood pressure changes produced by nociceptive stimulation.
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